Amphiphilic stilbene derivatives attenuate the neurotoxicity of soluble Aβ42 oligomers by controlling their interactions with cell membranes
| Autor: | Zhengxin Yu, Weijie Guo, Shrey Patel, Hong-Jun Cho, Liang Sun, Liviu M. Mirica |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Chemical Science. 13:12818-12830 |
| ISSN: | 2041-6539 2041-6520 |
| DOI: | 10.1039/d2sc02654f |
| Popis: | Amphiphilic compounds with selectivity towards soluble Aβ42 oligomers were developed. Cell imaging studies show the compounds can reduce the interactions between Aβ42 oligomers and SH-SY5Y cell membranes, both in the presence and absence of Cu. |
| Databáze: | OpenAIRE |
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