ChemInform Abstract: Design and Synthesis of a Novel Epoxide-Containing Pyrrolo(2,1-c) (1,4) benzodiazepine (PBD) via a New Cyclization Procedure

Autor:	David E. Thurston, Philip Wilson Howard, Stuart C. Wilson
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Benzodiazepine Chemistry medicine.drug_class Stereochemistry medicine Epoxide Moiety General Medicine
Zdroj:	ChemInform. 26
ISSN:	0931-7597
DOI:	10.1002/chin.199550139
Popis:	The synthesis of a potential DNA-crosslinking pyrrolo[2,1- c ][1,4]benzodiazepine (PBD) substituted at the C8-position with a 2,3-epoxypropaneoxy moiety using a new cyclization procedure is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5582b51cdb9d1a88a373a6b8bb250000 https://doi.org/10.1002/chin.199550139 Zobrazit plný text záznamu Plný text