The effect of therapy with olmesartan or telmisartan in patients with arterial hypertension combined with obesity

Autor: Yurij B Kuzminov, Andrij F Faynyk, Olesia Bochar, Helena Y Sklyarova, Volodymyr T Bochar, Andrij Y Bazylevych
Rok vydání: 2020
Předmět:
Zdroj: Wiadomości Lekarskie. 73:321-324
ISSN: 0043-5147
DOI: 10.36740/wlek202002122
Popis: OBJECTIVE The aim: To evaluate the hemodynamic and echocardiographic parameters, the level of adiponectin and IL-6 in such patients under the influence of therapy with sartans (telmisartan or olmesartan) and atorvastatin 12 weeks later. PATIENTS AND METHODS Materials and methods: Fifty patients with arterial hypertension of II stage and 2 level, who underwent elective in-patient treatment were examined. During the next 12 weeks, they took olmesartan (1st group) or telmisartan (2nd group) in combination with atorvastatin. RESULTS Results: The combined use of olmesartan or telmisartan in with atorvastatin for 12 weeks had a resulted in a significant decrease in systolic and diastolic blood pressure, heart rate and myocardial mass. After treatment with olmesartan in combination with atorvastatin, the adiponectin content in the blood increased by 41.6% (p
Databáze: OpenAIRE