Formation of molecular hydrogels from a bile acid derivative and selected carboxylic acids
| Autor: | Karen C. Waldron, X. X. Zhu, Meng Zhang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Hydrogen bond General Chemical Engineering Carboxylic acid Dimer Cholic acid 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Covalent bond Diethylenetriamine Self-healing hydrogels Organic chemistry Solubility 0210 nano-technology |
| Zdroj: | RSC Advances. 6:35436-35440 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/c6ra04536g |
| Popis: | Bile acids are natural compounds that can be made into dimers by covalently linking two of them through diethylenetriamine. A cholic acid dimer of this kind is synthesized and is found to form thermally reversible hydrogels with selected carboxylic acids through combined hydrogen bonding and ionic interactions. The gelation and viscoelastic properties of the hydrogels may be varied by judicious choice of the carboxylic mono- and diacids. The total organic content (the dimer and carboxylic acid) represents about 2% or less by weight in the ternary mixture. The molecular arrangement between the dimer and carboxylic acid is proposed to illustrate the formation mechanism of the hydrogels. The marginal solubility of the dimer–acid mixtures seems to be the deciding factor in obtaining the hydrogels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|