Reversible rhodamine-alkyne Au3+-selective chemosensor and its bioimaging application
| Autor: | Pailin Srisuratsiri, Palangpon Kongsaeree, Phongthon Kanjanasirirat, Arthid Chairongdua |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
Detection limit 010405 organic chemistry Organic Chemistry Alkyne 010402 general chemistry Photochemistry 01 natural sciences Biochemistry 0104 chemical sciences Rhodamine Job plot chemistry.chemical_compound Membrane chemistry Drug Discovery Propargyl Moiety Conjugate |
| Zdroj: | Tetrahedron Letters. 58:3194-3199 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2017.07.014 |
| Popis: | A rhodamine-alkyne conjugate has been developed for selective detection of Au 3+ in a reversible manner. Rhodamine was coupled with o- phenylenediamine bearing a propargyl moiety. The probe displayed high selectivity and sensitivity toward Au 3+ with a 148-fold “turn-on” fluorescence response in EtOH-H 2 O (1:1 v/v). The stoichiometry of the chemosensor and Au 3+ was 1:1 based on the Job plot analysis with the detection limit of 10.5 nM. The chemosensor is membrane permeable and capable of monitoring Au 3+ in cultured HeLa cells. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect