AgNO3-catalyzed decarboxylative cross-coupling reaction: an approach to coenzyme Q
Autor: | Bin Lu, Rong-Ye Zhou, Jin Wang, Luo Wanyue, Yong-Fu Qiu, He Yongjing |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | New Journal of Chemistry. 44:8702-8704 |
ISSN: | 1369-9261 1144-0546 |
Popis: | An efficient and general method for the synthesis of coenzyme Q compounds through the activation of the 1,4-benzoquinone Csp2–H bond has been developed. This C–C bond formation reaction proceeds readily in an open flask by the direct cross-coupling reaction of coenzyme Q0 with commercially available aliphatic carboxylic acids utilizing AgNO3 as a catalyst and K2S2O8 as an oxidant in aqueous solution. This radical reaction is operationally simple and amenable to gram-scale synthesis. |
Databáze: | OpenAIRE |
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