AgNO3-catalyzed decarboxylative cross-coupling reaction: an approach to coenzyme Q

Autor:	Bin Lu, Rong-Ye Zhou, Jin Wang, Luo Wanyue, Yong-Fu Qiu, He Yongjing
Rok vydání:	2020
Předmět:	Aqueous solution General method biology Chemistry Radical Decarboxylative cross-coupling General Chemistry Bond formation Combinatorial chemistry Catalysis Cofactor Coenzyme Q – cytochrome c reductase Materials Chemistry biology.protein
Zdroj:	New Journal of Chemistry. 44:8702-8704
ISSN:	1369-9261 1144-0546
Popis:	An efficient and general method for the synthesis of coenzyme Q compounds through the activation of the 1,4-benzoquinone Csp2–H bond has been developed. This C–C bond formation reaction proceeds readily in an open flask by the direct cross-coupling reaction of coenzyme Q0 with commercially available aliphatic carboxylic acids utilizing AgNO3 as a catalyst and K2S2O8 as an oxidant in aqueous solution. This radical reaction is operationally simple and amenable to gram-scale synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::552ef63e43d3fa17794b5de3bcdb536a https://doi.org/10.1039/d0nj01497d Zobrazit plný text záznamu