Diuretic activity of the bark of Eysenhardtia polystachya
| Autor: | María Estela Meléndez-Camargo, María Mirian Estévez-Carmona, Saudy Saret Pablo-Pérez |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
food.ingredient
Potassium medicine.medical_treatment Sodium chemistry.chemical_element Pharmacology 01 natural sciences Polystachya 03 medical and health sciences 0302 clinical medicine food medicine biology Furosemide biology.organism_classification Diuretic Activity 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry 030220 oncology & carcinogenesis visual_art Eysenhardtia polystachya visual_art.visual_art_medium Bark Diuretic medicine.drug |
| Zdroj: | Bangladesh Journal of Pharmacology. 11:212 |
| ISSN: | 1991-0088 |
| Popis: | The aim of this study was to evaluate the diuretic activity of Eysenhardtia polystachya bark aqueous extract at different doses in a rat model. Different doses of E. polystachya (125, 250, 500 and 750 mg/kg body weight), furosemide (4 mg/kg) and vehicle were administered per os to female rats (n=6 animals per group). After 6 hours in metabolic cages, the effect on urinary flow, glomerular filtration rate and electrolyte balance of sodium and potassium were assessed in all animals. E. polystachya at the doses of 500 and 750 mg/kg induced diuretic activity, since markedly increased (p E. polystachya bark-induced diuretic activity, providing evidence for its folkloric use. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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