DIARRHŒA AND PSEUDOMEMBRANOUS COLITIS AFTER GASTROINTESTINAL OPERATIONS
| Autor: | D. W. Burdon, H. Thompson, John Alexander-Williams, Mrb Keighley, Sandra Bentley, Y. Arabi, R.H. George, N. Shinagawa, Denise Youngs |
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| Rok vydání: | 1978 |
| Předmět: |
Enterocolitis
medicine.medical_specialty medicine.diagnostic_test medicine.drug_class business.industry digestive oral and skin physiology Antibiotics Rectum Sigmoidoscopy General Medicine Pseudomembranous colitis Clostridium difficile medicine.disease Gastroenterology fluids and secretions medicine.anatomical_structure Internal medicine Biopsy medicine Colitis medicine.symptom business |
| Zdroj: | The Lancet. 312:1165-1167 |
| ISSN: | 0140-6736 |
| Popis: | 241 patients who had gastrointestinal operations were studied prospectively. Postoperative diarrhoea occurred in 58 patients (24%) and was significantly more common after exposure to antibiotics. 9 patients (4%) had high titres of a neutralisable faecal toxin characteristic of pseudomembranous colitis. Toxigenic Clostridium difficile strains were isolated from the stools of all patients with neutralisable faecal toxin. If pseudomembranous colitis is defined as the presence of neutralisable faecal toxin, then the diagnosis is often missed by sigmoidoscopy and rectal biopsy. |
| Databáze: | OpenAIRE |
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