Popis: |
The changes in platelet parameters and the bleeding time during and following cardiopulmonary bypass (CPB) and their relationships to non-surgical blood loss following the administration of protamine were investigated in 85 adult male patients undergoing coronary artery and valvular heart surgery. The bleeding time was determined preoperatively, and 2, 24, 48, and 72 hours postoperatively. The blood shed from the site of the bleeding time determination was assayed for throbboxane B2 (shed blood TxB2) and 6-ketoprostaglandin F-1-alpha (shed blood 6-keto) levels. |