| Autor: |
Emanuele Micheli, Letizia Gianoncelli, Giovanni Luca Ceresoli, Maria Bonomi, Eleonora Cerchiaro, Elisa Villa, Lucia Setti |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Clinical Applications of Nuclear Medicine Targeted Therapy ISBN: 9783319630663 |
| DOI: |
10.1007/978-3-319-63067-0_25 |
| Popis: |
Bone metastases occur in more than 80% of men with metastatic prostate cancer. Affecting the structural integrity of the bone, they can lead to skeletal complications and pain, with a negative impact on patient quality of life and survival. The last decade has witnessed tremendous advances in the treatment of metastatic PCa. New therapeutic options that prolong overall survival are now available. The optimization of bone metastasis management (and prevention of skeletal morbidities) is therefore of paramount importance to improve clinical outcome. Some issues are still debated, such as the most effective radiologic or nuclear medicine technique to diagnose and monitor bone disease, the ideal surrogate circulating marker to assess response or progression to treatment, patient selection, as well as the optimal sequencing or combination of available therapeutic options. Several healthcare professionals play a role in the treatment of metastatic PCa. The presence of a multidisciplinary team for the discussion of treatment strategies for each patient should be the standard of care. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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