A practical guide to targeted therapy for bone pain palliation

Autor: Lewington Vj
Rok vydání: 2002
Předmět:
Zdroj: Nuclear Medicine Communications. 23:833-836
ISSN: 0143-3636
DOI: 10.1097/00006231-200209000-00004
Popis: Targeted radionuclide therapy is an effective and cost efficient treatment for multi-site metastatic bone pain. This paper discusses the physical characteristics of the licensed radiopharmaceuticals (153)Sm ethylenediamine-N,N,N',N'-tetrakis(methylene phosphonic acid) ((153)Sm-EDTMP), (186)Re 1,1-hydroxyethylidenediphosphonate ((186)Re-HEDP) and (89)SrCl(2) and considers the factors influencing treatment choice in specific clinical settings. The advantages and practical limitations of this approach are discussed, with emphasis on defining criteria for patient selection and response monitoring. Opportunities for future research and development are outlined.
Databáze: OpenAIRE