Immunohistochemical investigation of the Bursa of Fabricius in chickens experimentally infected by eimeria tenella
| Autor: | M Dimitrijevic Sanda, Ilic Tamara, A Knezevic Milijana, Aleksic-Kovacevic Sanja, D Nesic Vladimir |
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| Rok vydání: | 2004 |
| Předmět: |
0303 health sciences
education.field_of_study animal structures General Veterinary biology Lymphocyte 030302 biochemistry & molecular biology Population biology.organism_classification Virology Molecular biology Eimeria Epithelium 3. Good health 03 medical and health sciences medicine.anatomical_structure parasitic diseases biology.protein medicine Immunohistochemistry Bursa of Fabricius Antibody education 030304 developmental biology Peroxidase |
| Zdroj: | Acta veterinaria. 54:411-417 |
| ISSN: | 0567-8315 |
| DOI: | 10.2298/avb0406411i |
| Popis: | The aim of this investigation was to detect and examine the distribution of the CD3-T lymphocyte cell population of the Bursa Fabricius in chickens experimentally infected with Eimeria tenella. Slices of archived samples of Bursa were examined using the of direct peroxidase (DP) method. CD3-T lymphocytes were detected with human anti-CD3 antibody. They were localized in the cortico-medullary layer of Bursa follicles in uninfected chickens. The immunoreactivity of bursal tissue was directly correlated with the stage of development of E. tenella, with the highest intensity in the epithelium of the folds and in the layers of follicles between 3 and 5 days after the infection, predominantly in the cortico-medullary layer of the follicles. These results demonstrate the existence of an early cellular immunological response to infection with E. tenella. |
| Databáze: | OpenAIRE |
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