| Autor: |
Pawan Kumar Maurya, Lucas B. Rizzo, Elisa Brietzke, Ana S. Yamagata |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Neuroprogression in Psychiatry |
| DOI: |
10.1093/med/9780198787143.003.0003 |
| Popis: |
A convergent body of evidence suggests an overlap between neural, molecular, and functional findings in patients with severe mental illnesses and normative ageing. Patients in late stages of mood disorders and psychosis present brain changes and cognitive decline consistent with a pattern of accelerated ageing. In addition, replicated but heterogeneous findings support the notion that individuals with major depressive disorder, bipolar disorder, and schizophrenia have shorter telomeres compared to age-matched healthy controls. The recognition that severe mental illnesses are associated with premature or accelerated ageing offers new avenues of investigation for really novel therapeutic approaches. The hope is that these interventions will not only treat symptoms but be able to modify the course of these psychiatric conditions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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