Synthesis of 5-methylthioribose specifically bitritiated at the 5-C position
| Autor: | Christina Viegas, Georges Guillerm, Qiang Zhang, Danielle Guillerm |
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| Rok vydání: | 2001 |
| Předmět: |
chemistry.chemical_classification
Organic Chemistry Biochemistry Chemical synthesis humanities Analytical Chemistry chemistry.chemical_compound Enzyme 5-Methylthioribose kinase chemistry Drug Discovery Microbial enzymes Radiology Nuclear Medicine and imaging Methionine salvage pathway Spectroscopy 5-methylthioribose Derivative (chemistry) |
| Zdroj: | Journal of Labelled Compounds and Radiopharmaceuticals. 44:653-659 |
| ISSN: | 1099-1344 0362-4803 |
| Popis: | An efficient and reliable method for the preparation of bitritiated-methylthioribose from a suitably protected 5-ketoazido-ribose derivative has been developed. This compound is an essential component in the assay of the microbial enzyme methylthioribose kinase, which is involved in the methionine salvage pathway from methylthioadenosine. Copyright © 2001 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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