Sedierende Effekte von Extrakten ausHumulus lupulusL

Autor:	Hilke Winterhoff, Christian Vonhoff, Adrian Forster, Hartmut Schiller, Mirjam Hegger, Andreas Biller
Rok vydání:	2009
Předmět:	Pharmacology Elevated plus maze Humulus lupulus biology Traditional medicine Chemistry medicine.drug_class food and beverages biology.organism_classification Locomotor activity Anxiolytic Hop (networking) Complementary and alternative medicine Biochemistry medicine Medicinal plants Sleep duration
Zdroj:	Zeitschrift für Phytotherapie. 30:58-64
ISSN:	1438-9584 0722-348X
DOI:	10.1055/s-0029-1222464
Popis:	SEDATING EFFECTS OF HUMULUS LUPULUS L. EXTRACTSAlthough extracts from HUMULUS LUPULUS are traditionally used as sedating drugs, very few pharmacological studies have so far been performed. Ethanolic and CO 2 extracts from HUMULUS LUPULUS were tested for sedating activity in mice. Dosedependent reduction of locomotor activity and an increase in narcotica-induced sleep duration were observed, confirming sedation, whereas no indication of anxiolytic activity was seen in the Elevated Plus Maze test. The β-bitter acids were identified as the most effective constituens, but β-bitter acids and hop oil also proved to have a sedating effect.
Databáze:	OpenAIRE
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