The impact of bedding volumes on laboratory mice
| Autor: | Hansjoachim Hackbarth, Ping-Ping Tsai, H. D. Stelzer, Jennifer Freymann |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Food intake Bedding Ecology 05 social sciences Male mice Biology 03 medical and health sciences Food conversion 030104 developmental biology Animal science Food Animals Preference test medicine Home cage 0501 psychology and cognitive sciences Animal Science and Zoology 050102 behavioral science & comparative psychology medicine.symptom Weight gain |
| Zdroj: | Applied Animal Behaviour Science. 186:72-79 |
| ISSN: | 0168-1591 |
| Popis: | Environmental refinement is considered to be an improvement in housing conditions for laboratory animals. Previous preference tests showed that female BALB/c and C57BL/6 mice prefer deeper bedding in comparison to shallow bedding ( Freymann et al., 2015 ). In order to give a comprehensive insight into the impact of bedding depths on laboratory mice, we continued to examine the influence of three different bedding volumes (0.5 l, 1.5 l, 6 l) on the preference of male mice (experiment 1), home cage behaviour (experiment 2) as well as body temperature, food intake, food conversion efficiency (gram food intake per gram weight gain), intra-cage ammonia and corticosterone levels (experiment 3) of females and males. Experiment 1 used an automatic system to assess the preferences of male BALB/c and C57BL/6 mice. The bedding volumes were tested in pairs, which resulted in three test conditions (A = 0.5 l vs. 1.5 l; B = 0.5 l vs. 6 l; C = 1.5 l vs. 6 l). The results revealed significant preferences for cages containing large bedding volumes (test conditions A, B: p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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