Chemical Datasets, Antioxidant, Free Radicals Scavenger activities estimate in Aqueous Garlic (Allium sativum) extract

Autor:	Fatimah A. Jasim, Hameed Salman Al-Hilu
Rok vydání:	2021
Předmět:	Antioxidant Aqueous solution Chemistry medicine.medical_treatment Allium sativum extract medicine food and beverages Pharmacology (medical) Food science Free radicals scavenger Pharmacology Toxicology and Pharmaceutics (miscellaneous)
Zdroj:	Research Journal of Pharmacy and Technology. :5157-5162
ISSN:	0974-360X 0974-3618
DOI:	10.52711/0974-360x.2021.00897
Popis:	Garlic is one of many medicinal plants that used over thousands of years due to its organosulfur compounds. Materials and methods: commercial garlic was used for the extraction, phytochemicals detections and Gas Chromatography-Mass (GC- Mass) analysis utilized to determine the main compounds in the aqueous extract. Antioxidant activity was evaluated in the garlic extract using total antioxidant capacity (TAC) and DPPH for detecting the concentration that takes half of the free radicals. The phytochemical tests revealed several compounds in the extract, included alkaloid, glycosides, tannins, and flavonoid and phenol while saponin compound was not detected. GC-Mass spotted 15 different compounds included allyl trisulfide with the concentration (1.89%) followed by ascorbic acid 2, 6-dihexadecanoate (22.24%), 9, 12-Octadecadienoic acid (Z, Z) (11.44), and 6-Octadecenoic acid, (Z) (40, 28). Total Antioxidant Activity of garlic aqueous extract reached 60 mg/ml compared to that of ascorbic acid. IC50 examination observed that the aqueous extract of garlic had 308.57µg/ml value.
Databáze:	OpenAIRE
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