Non-Hodgkin's Lymphomas. Clinical Study of Waldeyer's Ring and Cervical Lymph Nodes

Autor:	Makito Okamoto, Meijin Nakayama, Katsuhide Inagi, Tomohiro Makoshi, Hiromi Nagai, Horoomi Takahashi, Kazuo Yao
Rok vydání:	2001
Předmět:	Chemotherapy medicine.medical_specialty Cyclophosphamide business.industry medicine.medical_treatment Pirarubicin Chemotherapy regimen Surgery Clinical study Waldeyer's ring medicine.anatomical_structure Otorhinolaryngology Cervical lymph nodes medicine Vindesine business medicine.drug
Zdroj:	Practica Oto-Rhino-Laryngologica. 94:65-69
ISSN:	1884-4545 0032-6313
DOI:	10.5631/jibirin.94.65
Popis:	Between June 1988 and December 1996, 57 patients with non-Hodgkin's lymphomas of the head and neck were treated at our department. The primary lesion was located in Waldeyer's ring in 31 patients and cervical lymph nodes in 26 patients. These patients, who were diagnosed as Stage I or II, were treated with chemotherapy and radiation. The chemotherapy regimen consisted of pirarubicin (45mg/m2; day 1), cyclophosphamide (750mg/m2; dayl), vindesine (1.5mg/m2; day 1) and predonisolone (100mg/body; days 1-5). The complete and partial response rates were 79% and 82% respectively. The five-year estimated overall survival rate calculated by Kaplan-Meier method was 75%. We concluded that the combination of chemotherapy regimen (THP-CVP) and radiation were useful and safe for treating non-Hodgkin's lymphomas of the head and neck.
Databáze:	OpenAIRE
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