Markers of efficacy of Infliximab in psoriasis patients
| Autor: | A A Kubanova, L F Znamenskaya, N V Frigo, I A Volkov, S V Rotanov, A V Rezaykina, A A KUBANOVA, L F ZNAMENSKAYA, N V FRIGO, I A VOLKOV, S V ROTANOV, A V REZAIKINA |
|---|---|
| Rok vydání: | 2011 |
| Zdroj: | Vestnik dermatologii i venerologii. 87:64-69 |
| ISSN: | 2313-6294 0042-4609 |
| DOI: | 10.25208/vdv1066 |
| Popis: | The article presents the results of molecular and genetic studies aimed at determination of molecular markers for forecasting the clinical response of psoriasis patients to treatment with Infliximab. The authors revealed that it is possible to forecast high efficacy of treatment with Infliximab in case TT genotype is revealed at the 676 locus of exon 6 of the TNF-RII gene and IL-10 is present in the blood serum prior to the onset of treatment in the amount of more than 2.7 pg/ml. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|