Synthesis and properties of novel hydrogels from oxidized pectin crosslinked gelatin for biomedical applications
Autor: | Asma Chetouani, Djafer Benachour, Mahmoud Bounekhel, Meriem Elkolli |
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Rok vydání: | 2014 |
Předmět: |
chemistry.chemical_classification
Thermogravimetric analysis food.ingredient Materials science Polymers and Plastics Pectin technology industry and agriculture macromolecular substances General Chemistry Condensed Matter Physics Aldehyde Gelatin food chemistry Chemical engineering Self-healing hydrogels Polymer chemistry Materials Chemistry Thermal stability Fourier transform infrared spectroscopy Triple helix |
Zdroj: | Polymer Bulletin. 71:2303-2316 |
ISSN: | 1436-2449 0170-0839 |
DOI: | 10.1007/s00289-014-1189-z |
Popis: | Gelatin (G) edible films with a new kind of dialdehyde polysaccharide, oxidized pectin (OP) as crosslinking agent are successfully prepared using casting techniques. FTIR and X-ray diffraction studies demonstrate that crosslinking is achieved through the reaction of aldehyde groups of oxidized pectin with the free amino groups in gelatin with a small affectation of the triple helix of gelatin. The qualitative and quantitative data about structures of films were determined by atomic force microscopy. Thermogravimetric analysis reveals that G/OP film has improved thermal stability in comparison with pure gelatin. Examination of the hemolytic potential showed that the obtained hydrogels are non-hemolytic in nature. These hydrogels are also nontoxic and blood-compatible. This kind of hydrogel is expected to be useful in the biomedical field, e.g., as wound dressing. |
Databáze: | OpenAIRE |
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