Cerebral Nocardiosis: a diagnostic challenge

Autor: Stella Pak, Adelina Martin, Rudoff Estess, Tamer Abdelhak
Rok vydání: 2023
Předmět:
Zdroj: Neurology Asia. 28:237-238
ISSN: 1823-6138
Popis: uncertain if this represented post-surgical change, residual neoplasm, radiation reaction, or infection. One-year after the brain mass resection, the patient presented to the hospital with new-onset expressive aphasia and focal weakness in the left lower extremity. Repeat MRI showed 3 new ring- enhancing lesions within the left cerebellum, left temporo-parietal junction, and left para-median superior parietal lobe (Figure 1). There was persistent irregular enhancement within the right cerebellum, now extending to the right middle cerebellar peduncle. Aspiration biopsy revealed a large amount of Nocardia farcinica, which was resistant to ceftriaxone, imipenem, clarithromycin, tobramycin, doxycycline, and minocycline. The patient was started on trimethoprim- sulfamethoxasole 400 mg three times/day, but despite continued antibiotic treatment, she became bacteremic. This was complicated by acute toxic
Databáze: OpenAIRE