Short Gut Syndrome
| Autor: | Austin Ge, Joseph K. Williams, Austin Ed, Maurice J. Jurkiewicz, Grant W. Carlson, Rand Rp |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
biology business.industry digestive oral and skin physiology Fissipedia biology.organism_classification Short bowel syndrome medicine.disease Small intestine Surgery Neovascularization Omentectomy Vascularity medicine.anatomical_structure Weight loss medicine Carnivora medicine.symptom business |
| Zdroj: | Annals of Plastic Surgery. 37:84-90 |
| ISSN: | 0148-7043 |
| Popis: | Surgical treatment for short bowel syndrome has been directed toward slowing intestinal transit or increasing the absorptive surface area of the bowel. In the present work, we attempted to enhance bowel absorption by increasing vascularity, using the omentum's unique ability to revascularize incorporated tissue. After a 90% resection of small bowel with primary anastomosis in 5 mongrel dogs, an omental flap based on the right gastroepiploic vessels was incorporated into a seromuscular incision on the antimesenteric border of the remnant small bowel. Five control dogs underwent a similar resection and seromuscular incision with an omentectomy. Serum d-xylose assays, hemoglobin, and total protein levels were measured preoperatively and at 3, 6, 9, and 12 weeks postoperatively. Weekly weights were followed. The mean percent d-xylose absorption in the experimental group increased from 96% of the baseline at 3 weeks to 136%, 163%, and 179% at 6, 9, and 12 weeks respectively (p < 0.5). The control group maintained absorption levels between 54% and 74%. Weight loss in the experimental group was significantly less than the controls at weeks 6 and 9, but by 12 weeks, weights were similar for the two groups. Small bowel absorption of d-xylose was significantly enhanced by incorporation of the omentum into the bowel remnant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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