Autor:	E. B. Nikol'skaya, B. N. Kormilitsyn, L. I. Kugusheva
Rok vydání:	2003
Předmět:	Detection limit Chromatography Potentiometric titration technology industry and agriculture macromolecular substances Analytical Chemistry chemistry.chemical_compound chemistry Biochemistry Muscarinic acetylcholine receptor medicine Choline Cholinergic Receptor Biosensor Acetylcholine medicine.drug
Zdroj:	Journal of Analytical Chemistry. 58:277-281
ISSN:	1061-9348
DOI:	10.1023/a:1022650823854
Popis:	A comparative assessment of the analytical capabilities of a tensoresistive biosensor based on muscarinic acetylcholine receptors and a potentiometric choline sensor was performed. It was found that the receptor biosensor is promising for the determination of ultratrace amounts of cholinergic agents with a detection limit of 10–7–10–10 M. The selectivity of the potentiometric choline sensor is equal to the selectivity of the receptor biosensor; however, the sensitivity of the former is lower by two orders of magnitude. Nevertheless, it can be successfully used for evaluating the relative receptor activity of cholinergic agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::540d333b83ef830817687254ebfc17b3 https://doi.org/10.1023/a:1022650823854 Zobrazit plný text záznamu Full text from SpringerLink