| Autor: |
V. Grishko, O. Naimark, Y. Bayandin, A. Nikityuk |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Perm Scientific Center Journal. 13:61-78 |
| ISSN: |
2658-705X |
| DOI: |
10.7242/2658-705x/2020.1.7 |
| Popis: |
The research is devoted to experimental and theoretical substantiation of the use of mechanobiological characteristics of cells as phenotypic markers of oncological pathologies. In the development of approaches related to the study of the mechanical state of cells in the «normal» and in the evolution of tumors, a comparative analysis has been carried out of the nonlinear dynamics of cell structures on the basis of the original data on the dynamics of «phase thicknesses» of cells obtained by coherent phase microscopy. The results of experimental studies have been generalized on the basis of epigenetic models reflecting mechanobiological features of cell and tissue structures in the development of cancer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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