Metal-free protocol for the synthesis of α-bromo ketones from olefins using TsNBr2

Autor:	Debojit Hazarika, Kamal Krishna Rajbongshi, Prodeep Phukan
Rok vydání:	2015
Předmět:	chemistry.chemical_classification Olefin fiber Ketone Metal free chemistry Yield (chemistry) Organic Chemistry Drug Discovery Organic chemistry Halogenation Biochemistry
Zdroj:	Tetrahedron Letters. 56:356-358
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2014.11.096
Popis:	TsNBr 2 reacts readily with olefins to produce α-bromo ketones at room temperature. The synthesis was carried out by treating an olefin with TsNBr 2 in acetone–water mixture in 30:1 ratio. Excellent yield of corresponding α-bromo ketone could be achieved within a short time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::53db04425320f57477e449cf93d74f23 https://doi.org/10.1016/j.tetlet.2014.11.096 Zobrazit plný text záznamu Full Text from ScienceDirect