Polysiloxanes as polymer matrices in biomedical engineering: their interesting properties as the reason for the use in medical sciences
| Autor: | Emmanuelle Perez, José Amir González Calderón, Javier Vallejo Montesinos, David Contreras López |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics Silicon technology industry and agriculture Skin treatments Polymeric matrix chemistry.chemical_element Nanoparticle 02 engineering and technology General Chemistry Polymer 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Drug penetration 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Siloxane Self-healing hydrogels Materials Chemistry 0210 nano-technology Biomedical engineering |
| Zdroj: | Polymer Bulletin. 77:2749-2817 |
| ISSN: | 1436-2449 0170-0839 |
| DOI: | 10.1007/s00289-019-02869-x |
| Popis: | Polysiloxanes have been found to be the most important and commercial family of synthetic inorganic polymers. The unique structure of the siloxane bond provides them with unusual features such as a high bond angle, nearly inexistent torsional barrier and a semi-ionic character due to the difference of electronegativities between the silicon and oxygen atoms. Also, silicon-based polymers have been used for the delivery of pharmaceutical and diagnostic compounds involving the use of nanoparticles with different shapes and sizes, as well as hydrogels, including those based on silicon compounds. Hydrogels based on silicon polyolates are rather promising. Some of them exhibit pronounced anti-inflammatory, regenerating, and protective activity, readily penetrate the organism and facilitate drug penetration into the tissues. Due to these properties, polysiloxanes have encountered a big opportunity as an important material in the area of biomedical engineering; the big influence they have in the area of prosthetic dentistry, tissue engineering, cell growth, wounded skin treatments is noteworthy. For the reasons briefly described above, we consider the fact of doing a review about how the polysiloxanes have been used over the years as polymeric matrices that are used in several applications in the field of biomedical engineering. |
| Databáze: | OpenAIRE |
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