Allium Chemistry: Synthesis of 1-[Alk(en)ylsulfinyl]propyl Alk(en)yl Disulfides (Cepaenes), Antithrombotic Flavorants from Homogenates of Onion (Allium cepa)

Autor:	Shu-Hai Zhao, Niannian You, Deyou Sha, Eric Block, Harsh Gulati, David Putman
Rok vydání:	1997
Předmět:	chemistry.chemical_compound chemistry biology Stereochemistry Antithrombotic Allium Sulfoxide Biological activity General Chemistry General Agricultural and Biological Sciences biology.organism_classification Aliphatic compound Chemical synthesis
Zdroj:	Journal of Agricultural and Food Chemistry. 45:4414-4422
ISSN:	1520-5118 0021-8561
Popis:	A series of 1-[alk(en)ylsulfinyl]propyl alk(en)yl disulfides (α-sulfinyl disulfides) of structure RS(O)CHEtSSR‘, R, R‘ = Me, (E,Z)-MeCHCH, n-Pr, and CH2CHCH2, termed cepaenes, have been synthesized by a variety of routes including oxidation of 1-[alk(en)ylthio]propyl alk(en)yl disulfides, RSCHEtSSR‘, termed deoxycepaenes. The cepaenes are identical to compounds isolated from homogenates of onion (Allium cepa) and to compounds identified in these homogenates by liquid chromatography/mass spectrometry, while the deoxycepaenes are identical to compounds found in Allium distilled oils and in other materials. The antithrombotic activities for several cepaenes are reported. Keywords: Allium chemistry; onion (Allium cepa); a-sulfinyl disulfides; cepaenes; antithrombotic compounds
Databáze:	OpenAIRE
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