Synthesis and membrane-protective activity of 4-aminomethyl derivatives of 2,6-diisobornylphenol

Autor:	A. V. Kutchin, K. Yu. Suponitskii, Evgeny V. Buravlev, I. Yu. Chukicheva, Oksana G. Shevchenko
Rok vydání:	2017
Předmět:	Antioxidant 010405 organic chemistry medicine.medical_treatment Substituent General Chemistry Test object 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Membrane chemistry Toxicity medicine Organic chemistry
Zdroj:	Russian Chemical Bulletin. 66:91-98
ISSN:	1573-9171 1066-5285
Popis:	A series of 4-aminomethyl derivatives of 2,6-diisobornylphenol containing tertiary and secondary amino groups were synthesized. Their toxicity and the membrane-protective and antioxidant activity were assessed using red blood cells of laboratory mice as the test object. These compounds were shown to exhibit high membrane-protective and antioxidant activity, which substantially depends on the structure of the substituent and the concentration of the substance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5395e4188e7c303cedd5981bd938429e https://doi.org/10.1007/s11172-017-1705-z Zobrazit plný text záznamu Full text from SpringerLink