JetGene: Internet Resource for Analysis of Regulatory Regions or Nucleotide Contexts in Differentially Translated Plant Transcripts

Autor:	A. A. Tyurin, O. N. Mustafaev, I. V. Deineko, N. S. Sadovskaya, I. V. Goldenkova-Pavlova
Rok vydání:	2021
Předmět:	Untranslated region Translational efficiency Start codon business.industry Regulatory sequence In silico Complementary DNA Context (language use) The Internet Plant Science Computational biology Biology business
Zdroj:	Russian Journal of Plant Physiology. 68:633-640
ISSN:	1608-3407 1021-4437
Popis:	Various regulatory codes contained in mRNA can determine the fate of any transcript during translation. To search for similar regulatory codes and study their impact on translational efficiency, we have developed the JetGene Internet resource ( https://jetgene.bioset.org/ ). It contains CDS, cDNA, 5'‑UTR, and 3'‑UTR sequences from six major groups of living organisms, including plants. This internet resource has a user-friendly interface, puts together a wide range of tools for comparative analysis of nucleotide sequences and allows one (1) to estimate variations of length, nucleotide composition, and codon frequency, to analyze GC-content, CpG-islands, start codon context, etc..; (2) to identify and determine the statistically significant representation of potential regulatory contexts at mRNA with different translational efficiency. A user can make versatile in silico analysis of full-length or truncated transcripts as well as their coding or noncoding regions. Every step of the analysis is accompanied by a graphical interpretation of the results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5373956dc9f110a7267ff7758a5e8882 https://doi.org/10.1134/s1021443721040142 Zobrazit plný text záznamu Plný text ve formátu PDF