Chemiluminescence determination of some local anaesthetics

Autor: X. R. Zhang, Antony C. Calokerinos, G. Van der Weken, Willy R. G. Baeyens, Kazuhiro Imai
Rok vydání: 1995
Předmět:
Zdroj: Analytica Chimica Acta. 303:137-142
ISSN: 0003-2670
DOI: 10.1016/0003-2670(94)00517-p
Popis: The analytical possibilities of the Chemiluminescence observed from some local anaesthetics on acidic permanganate treatment are investigated. Five drugs belonging to the p-aminobenzoate series gave significant emission and the reagent concentrations for their determination were optimized. The following detection limits were obtained: benzocaine, 30 ng ml−1; butacaine, 20 ng ml−1; butoform, 30 ng ml−1; procaine, 40 ng ml−1 and tetracaine 3 ng ml−1. The application of the reaction to the analysis of some pharmaceutical preparations containing benzocaine and procaine was evaluated.
Databáze: OpenAIRE