Combined peripheral and central chemoembolization of liver tumors.Experience with lipiodol-doxorubicin and gelatin sponge (L-TAE)

Autor: Yoshiyuki Shimamura, Akira Takahashi, Yoshifumi Takenaka, Kazuhiro Arima, Peter Gunvén, Hisakazu Shimizu, Hiroshi Hasegawa, Tomoji Matsuyama, Yasuo Shima, Hiroshi Akimoto, Tomoki Kitaya
Rok vydání: 1988
Předmět:
Zdroj: Cancer. 61:238-242
ISSN: 1097-0142
0008-543X
Popis: Patients with primary and a few with secondary liver tumors were embolized through the hepatic artery. Lipiodol and doxorubicin occluded peripherally, which was immediately followed by central embolization with gelatin sponge cubes. Preoperative embolizations were made for diagnostic and possible surgical adjuvant purposes. Extensive postembolization necrosis was common in tumors less than 5 cm in diameter, and tumor markers usually decreased temporarily after treatment. There were moderate side effects of pain, fever and nausea, and an acceptable complication and mortality rate with no deaths after embolization alone. This warrants further research on the method, which also seemed to improve the detection rate for small hepatocellular carcinomas.
Databáze: OpenAIRE