Use of multiple channel pH monitoring for evaluation of ultra-distal reflux in patients after fundoplication for treatment of Barrett's esophagus
| Autor: | Humberto Kishi, Sergio Szachnowicz, Ary Nasi, Marco Aurelio Santo, F. Maluf Filho, Rubens Antonio Aissar Sallum, Francisco Carlos Bernal da Costa Seguro, Ângela Marinho Falcão, Ivan Cecconello |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry medicine.medical_treatment Gastroenterology Reflux General Medicine Nissen fundoplication medicine.disease Ph monitoring digestive system diseases Endoscopy medicine.anatomical_structure Dysplasia Barrett's esophagus Internal medicine otorhinolaryngologic diseases medicine Esophagus Esophageal pH monitoring business |
| Zdroj: | Diseases of the Esophagus. 24:381-387 |
| ISSN: | 1120-8694 |
| DOI: | 10.1111/j.1442-2050.2010.01160.x |
| Popis: | Dysplasia and esophageal adenocarcinoma may arise in patients with Barrett's esophagus after fundoplication esophageal pH monitoring showing no acid in esophagus. This suggests the need to develop methodology to evaluate the occurrence of ultra-distal reflux (1cm above the LES). The objective of the study was to compare acid exposition in three different levels: 5cm above the upper border of the LES, 1cm above the LES and in the intrasphincteric region. Eleven patients with Barrett's esophagus after Nissen fundoplication with no clinical, endoscopic and radiologic evidence of reflux were selected. Four-channel pH monitoring took place: channel A, 5cm above the upper border of the LES; channel B, 1cm above the LES; channel C, intrasphincteric; channel D, intragastric. The results of channels A, B and C were compared. There was significant increase in number of reflux episodes and a higher fraction of time with pH |
| Databáze: | OpenAIRE |
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