COMPARISON OF THE INFLUENCES OF ADRENOCORTICAL HORMONES ON THE GROWTH AND INVOLUTION OF LYMPHATIC ORGANS1,2,3

Autor:	Thomas F. Dougherty, George A. Santisteban
Rok vydání:	1954
Předmět:	medicine.medical_specialty Adrenal cortex hormones Biology Lymphatic tissues Endocrinology Lymphatic system medicine.anatomical_structure Internal medicine medicine Lymphatic vessel Involution (medicine) Cortisone medicine.drug Hormone
Zdroj:	Endocrinology. 54:130-146
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-54-2-130
Popis:	PRELIMINARY investigations of the acute involution of lymphatic organs induced by administration of cortisone demonstrated that the hormone-induced involution of lymphatic tissue was a response of the continuous variate type (Santisteban, 1953). Accordingly, more detailed studies were performed to ascertain whether the regression relationships of certain lymphatic organs could be employed to elucidate further the quantitative interrelationships of amounts and molecular structures of certain adrenocortical hormones to the growth and involution of lymphatic organs. Although the method presented here might be adapted to various types of bioassay procedures, the emphasis in these studies has been directed towards establishing the comparative potencies and structural activity relationships of those adrenocortical hormones which were known to have the capacity to induce acute lymphatic organ involution (reviewed by Dougherty, 1952). Other steroid hormones which have been reported by various authors to produce g...
Databáze:	OpenAIRE
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