Efficacy of povidone iodine as a disinfectant at the donor phlebotomy site
| Autor: | Takako Mitani, Hiroshi Hashimoto, Sadayoshi Sekiguchi, Masaaki Chiba |
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| Rok vydání: | 1999 |
| Předmět: | |
| Zdroj: | Journal of the Japan Society of Blood Transfusion. 45:20-25 |
| ISSN: | 1883-8383 0546-1448 |
| Popis: | We evaluated the efficacy of two skin disinfectants (10% povidone iodine vs. 0.5% chlorhexidine gluconate) at the donor phlebotomy site against three different species of bacteria (Bacillus cereus, coagulase-negative staphylococci, Propionibacterium acnes).The growth of Bacillus cereus in apheresis-derived platelet concentrates was very rapid with a doubling time of 6 hours, and reached 107CFU/ml within 72 hours. When RC-MAP prepared from whole blood inoculated with Bacillus cereus was stored at 4°C, growth of Bacillus cereus was stopped for 21 days. However, when storage temperature was increased to 22°C on Days 7 or 21, rapid proliferation occurred as was observed in apheresis-derived platelets experiments. Bacterial proliferation was also observed in buffy coat and platelet-poor plasma prepared from whole blood.No difference was seen between 10% povidone iodine and 0.5% chlorhexidine gluconate in the efficacy of disinfectants against coagulase-negative staphylococci and Propionibacterium acnes. However, disinfection of Bacillus cereus was achieved with 10% povidone iodine only.Bacillus cereus showed proliferation in all blood components. These results suggest that donor skin disinfectant should be done using 10% povidone iodine in any blood collection. |
| Databáze: | OpenAIRE |
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