Short Communication
| Autor: | Linda Masat, Matthias Wabl |
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| Rok vydání: | 1997 |
| Předmět: | |
| Zdroj: | Biological Chemistry. 378 |
| ISSN: | 1437-4315 1431-6730 |
| Popis: | The Na,K-ATPase, or sodium pump, a ubiquitous transmembrane enzyme in higher eukaryotes, consists of an alpha and a beta subunit. Here we investigate the expression pattern of the two beta isotypes in mouse B cell lines. Neither primary cells nor cell lines express beta 2. Abelson virus-transformed pre-B cells express beta 1, while B lymphomas and plasmacytomas do not. Thus, beta 1 expression in transformed cells follows that of their untransformed counterparts. Some subclones of pre-B cell line 70Z/3 express beta 1, and others do not, but lipopolysaccharide induces the beta 1-negative cells to become beta 1-positive. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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