Transcriptome profiling implicated in beneficiary actions of kimchi extracts against Helicobacter pylori infection
| Autor: | Ji Young Oh, Ki Baik Hahm, Young-Min Han, Dong-Yoon Lee, Jong Min Park, Seung Hye Choi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Nutrition and Dietetics
biology Atrophic gastritis Clinical Biochemistry Medicine (miscellaneous) Cancer Helicobacter pylori bacterial infections and mycoses biology.organism_classification medicine.disease medicine.disease_cause Microbiology Transcriptome PTPRN Apoptosis medicine KEGG Oxidative stress |
| Zdroj: | Journal of Clinical Biochemistry and Nutrition. 69:171-187 |
| ISSN: | 1880-5086 0912-0009 |
| DOI: | 10.3164/jcbn.20-116 |
| Popis: | Dietary intervention to prevent Helicobacter pylori (H. pylori)-gastric cancer might be ideal because of no risk of bacterial resistance, safety, and rejuvenating action of atrophic gastritis. We have published data about the potential of fermented kimchi as nutritional approach for H. pylori. Hence recent advances in RNAseq analysis lead us to investigate the transcriptome analysis to explain these beneficiary actions of kimchi. gastric cells were infected with either H. pylori or H. pylori plus kimchi. 943 genes were identified as significantly increased or decreased genes according to H. pylori infection and 68 genes as significantly changed between H. pylori infection and H. pylori plus kimchi (p |
| Databáze: | OpenAIRE |
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