11C-carbonylation reactions using gas–liquid segmented microfluidics

Autor: Christer Halldin, Johan Ulin, Carl-Olof Sjöberg, Lars Farde, Magnus Schou, Kenneth Dahl
Rok vydání: 2015
Předmět:
Zdroj: RSC Advances. 5:88886-88889
ISSN: 2046-2069
Popis: A novel gas–liquid segmented microfluidic platform has been developed. The Pd-mediated 11C-carbonylation reaction proceeds smoothly on this platform and good to excellent radiochemical conversions (RCC) were observed. Twelve compounds were successfully radiolabelled using this novel technology, including the well established D2 receptor radioligands [11C]raclopride and [11C]FLB 457.
Databáze: OpenAIRE