The role of hepcidin in the main iron-deficiency syndromes in pregnancy
| Autor: | E V Demikhova, O N Zhourina, V G Demikhov, E N Zinovyeva, I M Mirov, M Ayari |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Pregnancy biology Anemia business.industry nutritional and metabolic diseases Physiology Iron deficiency medicine.disease Ferritin Endocrinology Iron-deficiency anemia Hepcidin Erythropoietin hemic and lymphatic diseases Internal medicine medicine biology.protein Erythropoiesis business medicine.drug |
| Zdroj: | I.P.Pavlov Russian Medical Biological Herald. 24:96-103 |
| ISSN: | 2500-2546 0204-3475 |
| DOI: | 10.23888/pavlovj2016496-103 |
| Popis: | Currently, there is evidence that hepcidin is the main regulator of iron metabolism in human and pathogenesis key factor for anemia of inflammation. However, the role of hepcidin in multifactorial pathogenesis of anemia in pregnancy is not clear. We presented the results of the laboratory examinations of 78 pregnant women sera in hepcidin, ferritin, erythropoietin during pregnancy, and 116 sera of pregnant women with iron deficiency anemia (IDA) and anemia of mixed origin. The obtained data indicate a statistically significant decrease in the mean hepcidin concentration in pregnants versus non pregnant women. Mean hepcidin level in pregnant women with IDA was decreased, compared with anemia of mixed origin pregnants (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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