Block Copolymers of Methoxypoly(Ethylene Oxide) and Poly(ϵ-Caprolactone): Synthesis, Structure, Micellization, and Interaction with Prednisolon
| Autor: | Alexey Kolendo, Sofia Partsevskaya, Tatyana Zheltonozhskaya, N. M. Permyakova, Vitaliy V. Khutoryanskiy |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Materials science
Aqueous solution Ethylene oxide medicine.diagnostic_test Hydrogen bond General Chemistry Condensed Matter Physics chemistry.chemical_compound chemistry Spectrophotometry Polymer chemistry medicine Copolymer General Materials Science Static light scattering Fourier transform infrared spectroscopy Glass transition |
| Zdroj: | Molecular Crystals and Liquid Crystals. 536:215/[447]-223/[455] |
| ISSN: | 1563-5287 1542-1406 |
| DOI: | 10.1080/15421406.2011.538610 |
| Popis: | A series of MOPEO-b-PCL diblock copolymers (DBCs) with M nMOPEO = 2.5 · 103 and M nPCL = (0.28 ÷ 2.43) · 104 was synthesized using the anionic ring-opening block copolymerization. A bulk structure of the copolymers was studied with DSC. One glass transition and three melting peaks for MOPEO-b-PCL were found, thus implying the existence of separate crystalline domains of both blocks in a copolymer structure. The intense micellization of DBCs in dioxane/aqueous solutions was found with a spectrophotometry, a static light scattering, and photography. A reduction in CMC and an increase in −ΔG° values with growth of the PCL length and at the addition of prednisolon (PS) were established. The hydrogen bonding of PS with DBCs was confirmed with FTIR spectroscopy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|