CONCOMITANT INFECTION OF LEPTOSPIROSIS WITH DENGUE AT A TERTIARY CARE HOSPITAL IN CHENNAI
| Autor: | B. Ananthi, G. Sumathi |
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| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Journal of Evolution of Medical and Dental Sciences. 3:1823-1827 |
| ISSN: | 2278-4802 2278-4748 |
| DOI: | 10.14260/jemds/2014/2063 |
| Popis: | BACKGROUND: Concomitant infection of leptospirosis with dengue has been reported in places where these diseases are endemic and leptospirosis may be overlooked in such cases. Recognition of leptospirosis is especially important since antimicrobial agents can reduce its severity and duration. Failure to identify leptospirosis in these patients will result in high mortality rate for this infection. Hence this study was conducted to have a detailed knowledge and awareness about the concomitant infection of leptospirosis with dengue. MATERIALS AND METHODS: Patients admitted to the medical ward of Government General Hospital, Chennai with fever of ≥ 5days and of the age group twelve years and above were evaluated for leptospirosis by doing the screening test MSAT (Macroscopic Slide Agglutination Test). All patients who tested positive for MSAT were further confirmed by MAT (Microscopic Agglutination Test). Those patients who tested positive for leptospirosis were investigated for concomitant infection with dengue utilising IgM ELISA. Patients positive for both leptospirosis and dengue were taken up for the study and were evaluated for relevant clinical features and laboratory profile. RESULTS: 143 patients were found to be positive for leptospirosis and among them 4 (2.8%) patients were positive for the concomitant dengue infection. In the four concomitant infection patients, two were males and two were females, all in the age group of 20 to 30 years. Fever and myalgia were the predominant symptoms in these patients. Thrombocytopenia was seen in 3 (75%) patients. With fluid resuscitation, platelet transfusion, appropriate drug and supportive therapy all the four patients recovered. No mortality was observed in this study. CONCLUSION: Increased awareness of concomitant infection and an enhanced ability to diagnose it early in illness is necessary so that appropriate treatment and supportive measures can be given to reduce the morbidity and mortality. Leptospiral illness may be a significant component in patients with concomitant infections and hence it is essential to evaluate for leptospirosis in all |
| Databáze: | OpenAIRE |
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