Histopathological Interpretation Of Colonic Mucosal Biopsies With Clinical Correlation: A Study In A Tertiary Care Hospital Kerala
| Autor: | Abilash Sasidharannair Chandrakumari, Shreelakshmidevi Singaravelu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Abdominal pain Pathology Constipation medicine.diagnostic_test business.industry H&E stain Rectum Colonoscopy medicine.disease Gastroenterology Ulcerative colitis digestive system diseases medicine.anatomical_structure Internal medicine medicine General Earth and Planetary Sciences Histopathology Colitis medicine.symptom business General Environmental Science |
| Zdroj: | Annals of Pathology and Laboratory Medicine. 4:A565-A572 |
| ISSN: | 2349-6983 2394-6466 |
| Popis: | Background: Colon is the most common site for various diseases. Diseases affecting the colon may cause abdominal pain, constipation, diarrhea and bleeding per rectum. Colonoscopy is endoscopic examination of the colon with a flexible optic fibers, this method allows visual examination of colonic mucosa and provides opportunity for mucosal biopsies. This study was carried out to study and correlate histopathological spectrum of colonic mucosal biopsies with clinical findings.Methods: This two years study was conducted during the period of April 2015 to March 2017. 250 colonoscopic biopsies were included in the study. All biopsies were fixed in formalin, processed as per routine histopathology processing, stained with Hematoxylin & Eosin stains and studied.Results: Out of 250 colonoscopic biopsies, 152 were non-neoplastic and 98 were neoplastic. Non neoplastic lesions were found to affect the colon most commonly. Most of the cases with non-neoplastic lesions presented with colicky abdominal pain, diarrhea and constipation. Among neoplastic lesions, 44 cases were benign and 54 cases were malignant. Majority of cases with neoplastic lesions presented with bleeding per rectum and constipation.Conclusion: Non neoplastic lesions were found to affect the colon most commonly. This study emphasize the increase in incidence of ulcerative colitis and colorectal carcinomas. Histopathological interpretation on colonic mucosal biopsies has taken a cornerstone in the diagnosis and management of patients with colonic lesions.DOI:10.21276/APALM.1534 |
| Databáze: | OpenAIRE |
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