Synthesis and Insecticidal Activity of Novel Thiazole Acrylonitrile Derivatives

Autor:	Huang Lu, Yeguo Ren, Cao Shengwen, Liu Weidong, Hui Pei, Zheng Xi, Daoxin Wu, Aiping Liu, Mingzhi Huang, Xingping Liu
Rok vydání:	2017
Předmět:	010405 organic chemistry Stereochemistry Organic Chemistry 010402 general chemistry Mass spectrometry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Bioassay Organic chemistry Potency Acrylonitrile Thiazole
Zdroj:	Journal of Heterocyclic Chemistry. 54:3395-3402
ISSN:	0022-152X
DOI:	10.1002/jhet.2961
Popis:	A series of novel thiazole acrylonitrile derivatives was designed and synthesized utilizing NC-510 as a precursor. Their structures were characterized by NMR spectrometry, MS, and elemental analysis. The results of bioassay indicated that some of these title compounds exhibited 100% mortality at 50 mg/L against Aphis fabae. In particular, the compound 11c displayed the best activity: Its LC50 value achieved 1.45 mg/L, and its insecticidal potency is comparable with that of NC-510.
Databáze:	OpenAIRE
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