A multiple-step screening protocol to identify norepinephrine and dopamine reuptake inhibitors for depression
| Autor: | Panpan Wang, Fengmei Yan, Jianghong Dong, Shengqiang Wang, Yu Shi, Mengdan Zhu, Yuting Zuo, Hui Ma, Ruirui Xue, Dingjie Zhai, Xiaoyu Song |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Physical Chemistry Chemical Physics. 25:8341-8354 |
| ISSN: | 1463-9084 1463-9076 |
| Popis: | A comprehensive strategy was used that identified six novel NDRIs from compound libraries that were selective against hNET and hDAT. Five compounds showed high activities, and four of them performed balancing activities acting on hNET and hDAT. |
| Databáze: | OpenAIRE |
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