Central corneal thickness and its associations in a Russian population. The Ural eye and Medical Study

Autor: Mukharram M. Bikbov, Timur R. Gilmanshin, Rinat M. Zainullin, Gyulli M. Kazakbaeva, Artur F. Zaynetdinov, Ildar F. Nuriev, Songhomitra Panda-Jonas, Inga I. Arslangareeva, Ainur A. Zinnatullin, Dilya F. Yakupova, Ellina M. Rakhimova, Yulia V. Uzianbaeva, Renat I. Khikmatullin, Nikolay A. Nikitin, Said K. Aminev, Svetlana R. Mukhamadieva, Venera F. Mavlieva, Jost B. Jonas
Rok vydání: 2022
Předmět:
Zdroj: Eye. 37:705-713
ISSN: 1476-5454
0950-222X
Popis: Background To assess central corneal thickness (CCT) and its associations in a Russian population. Methods The population-based Ural Eye and Medical Study included 5899 (80.5%) out of 7328 eligible individuals. As part of an ophthalmological and general examination, CCT was measured by Scheimflug imaging. Results The study included 5792 (98.2%) participants (age:58.8 ± 10.6 years;range: 40–94 years) with available bilateral CCT measurements. Mean CCT was larger in Russians than non-Russians (549.5 ± 32.8 µm versus 539.2 ± 33.9 µm; P P P = 0.002), urban region of habitation (beta:0.10; B:6.83; 95%CI:4.61, 9.05; P P = 0.005), higher level of education (beta:0.04; B:0.97;95%CI:0.29,1.66; P = 0.006), higher serum bilirubin concentration (beta:0.05;B:0.15; 95%CI:0.07,0.23;P P P P P P = 0.14), previous cataract surgery (P = 0.10), axial length (P = 0.18) or prevalence of glaucoma (P = 0.11). The mean inter-eye difference in CCT was 8.52 ± 13.9 µm (median:6.0;95CI:8.16,8.88). A higher inter-eye CCT difference was associated with older age (beta:0.08; B:0.11;95%CI:0.07,0.15; P = 0.01), lower level of education (beta:−0.04;B:−0.34; 95%CI:−0.60,−0.08; P P = 0.003). Introduction conclusions In this ethnically mixed population from Russia with an age of 40+ years, mean CCT (541.7 ± 33.7 µm) was associated with parameters such as younger age, male sex, Russian ethnicity, and higher educational level. These associations may be taken into account when the dependence of IOP readings on CCT are considered. Glaucoma prevalence was unrelated to CCT.
Databáze: OpenAIRE
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