Molecular evidence of tuberculosis induced hypertrophic osteopathy in a 16th-century Iroquoian dog

Autor: Rhonda R. Bathurst, Jodi Lynn Barta
Rok vydání: 2004
Předmět:
Zdroj: Journal of Archaeological Science. 31:917-925
ISSN: 0305-4403
DOI: 10.1016/j.jas.2003.12.006
Popis: A fully articulated dog skeleton excavated from a 16th-century Neutral Iroquoian site in Ontario, Canada displays a distinctive osteological condition known as hypertrophic osteopathy (HPO). Ancient DNA (aDNA) analysis of the dog has isolated Mycobacterium tuberculosis complex DNA, linking the secondary condition of HPO to tuberculosis (TB) and representing the oldest known case of TB yet to be discovered in the domestic dog. We emphasize that dogs should be considered as potential reservoirs of TB into the Americas.
Databáze: OpenAIRE