Radioaerosol Scintigraphy in Infants and Children Born to Mothers with HIV Disease

Autor: H. H. Peavy, D. C. P. Chen, C. K. Kim, V. W. Lee, Salvador Treves, A. Shah, John H. Miller, Carl K. Hoh, M. J. Fleishman, W. H. Moore, Philip O. Alderson, R. B. Mellins
Rok vydání: 1999
Předmět:
Zdroj: Radiology. 210:815-822
ISSN: 1527-1315
0033-8419
DOI: 10.1148/radiology.210.3.r99mr09815
Popis: PURPOSE: To determine the usefulness of technetium 99m diethyltriaminepentacetic acid (DTPA) radioaerosol inhalation-clearance scintigraphy for early detection of pulmonary complications of human immunodeficiency virus (HIV) disease in children. MATERIALS AND METHODS: A total of 301 studies were performed in 132 HIV-positive children (group 1; mean age, 46.6 months). In children born to HIV-positive mothers (group 2), 273 studies were performed in 160 children who eventually were proved to be HIV negative (mean age, 10.3 months), and 80 studies were performed in 47 HIV-positive children (mean age, 15.6 months). Radioaerosol studies were performed by using commercially available radioaerosol nebulizers. Pulmonary clearance half-time was measured by using conventional gamma camera computer systems. Radioaerosol results were correlated with indexes of pulmonary health and function. RESULTS: The HIV-negative, group 2 children had a mean radioaerosol clearance half-time (58.1 minutes; 162 studies in 108 childr...
Databáze: OpenAIRE