α‐Fetoprotein Producing Early Gastric Cancer
| Autor: | Yutaka Aoyagi, Seiji Sakurai, Toshirou Ikeya, Shoji Yamada, Takehiko Abe, Hitoshi Takagi, Setsuo Kobayashi |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
Pathology Liver tumor business.industry medicine.medical_treatment digestive oral and skin physiology Gastroenterology Cancer medicine.disease digestive system diseases Early Gastric Cancer Hepatocellular carcinoma Internal medicine embryonic structures Tubular Adenocarcinoma Medicine Orchitis Radiology Nuclear Medicine and imaging Gastrectomy Differential diagnosis business neoplasms |
| Zdroj: | Digestive Endoscopy. 3:368-372 |
| ISSN: | 1443-1661 0915-5635 |
| Popis: | A 53-year-old male suspected of having a testicular tumor associated with a moderately high titer of α-Fetoprotein (AFP), was shown to have a IIa + IIc type early gastric cancer in the cardia. The urological diagnoses made from the operated specimen were orchitis and epididimitis. Because of the moderately high titer of AFP (30–80 ng/ml), it was suspected that he had a hepatocellular carcinoma (HCC). A routine upper gastrointestinal endoscopy performed prior to the celiac angiography to assess for a liver tumor revealed gastric cancer. HCC was ruled out using celiac angiography and a total gastrectomy was performed. The operative findings of: P0 H0 N4 S0 corresponded with stage IV gastric cancer. Subsequently his AFP decreased to an undetectable level and the patient is in a good postoperative condition. The resected tumor was a well differentiated tubular adenocarcinoma and stained positive for AFP. A differential diagnosis with the subtype of AFP excluded the possibility of a yolk sac tumor but did not permit differentiation of the HCC from gastric cancer. A diagnosis of AFP producing gastric cancer must be carefully considered when HCC has been excluded in patients with high AFP titers. |
| Databáze: | OpenAIRE |
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