Antimicrobial Susceptibility Pattern of Pseudomonas aeruginosa isolated from Clinical and Environmental Sources in Punjab, Pakistan
| Autor: | Muhammad Kamran, Muhammad Adil Choudary, Haroon Amin, Samra Asghar, Adeel Shahid, Saba Zafar, Hamza Javed, Muhammad Hassan Sarfraz, Mohsin Khurshid |
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| Rok vydání: | 2022 |
| Zdroj: | Pakistan BioMedical Journal. :80-84 |
| ISSN: | 2709-2798 2709-278X |
| Popis: | The increasing incidence of antimicrobial resistance is a public health concern, and Pseudomonas aeruginosa is known to be resistant to a variety of antibiotics. Antimicrobial resistance and the multiple antibiotic resistance (MAR) index of P. aeruginosa from environmental and clinical sources were studied in the current study. A total of 170 samples were evaluated, with 85 samples each from environmental sources and clinical settings. The isolates were subjected to microbial analysis and antimicrobial sensitivity testing. The findings revealed that 45.88 % (39) of the 85 clinical isolates tested for the presence of P. aeruginosa were positive. In terms of prevalence, there were significant variations (p 0.05) between the clinical samples. Wound samples had the highest isolation rate of 28.2%, while urine samples had the lowest (12.8%). P. aeruginosa was found in 38.8 % (33/85) of the samples isolated from environmental sources. In terms of prevalence, there was a highly significant difference (p 0.01) between the isolates. All of the positive isolates were completely resistant to cefuroxime and amoxicillin (100 %). The majority were also resistant to, cotrimoxazole (82%), nalidixic acid (82%), ciprofloxacin (86%), and tobramycin (69%). There was a substantial variation in the resistance patterns of isolates. The current study demand comprehensive measure to combat antimicrobial resistance in P. aeruginosa. |
| Databáze: | OpenAIRE |
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