Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos
| Autor: | Pedro Muniesa, Ana M. Lacosta, Jesús Ruberte, Manuel Sarasa, Luis Domínguez |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Neural fold
animal structures Clinical Biochemistry PAX3 Neural crest Ectoderm Embryo Cell Biology Plant Science Anatomy Biology Melanocyte musculoskeletal system Quail Cell biology medicine.anatomical_structure biology.animal embryonic structures medicine PAX7 tissues Agronomy and Crop Science Developmental Biology |
| Zdroj: | Pigment Cell Research. 18:243-251 |
| ISSN: | 1600-0749 0893-5785 |
| DOI: | 10.1111/j.1600-0749.2005.00238.x |
| Popis: | Neural crest cells are considered a key vertebrate feature that is studied intensively because of their relevance to development and evolution. Here we report the expression of Pax7 in the dorsal non-neural ectoderm and in the trunk neural crest of the early chick embryo. Pax7 is expressed in the trunk neural crest migrating along the ventral and dorsolateral routes. Pax7 is first downregulated in the neural crest-derived neuronal precursors, secondly in the glial, and finally in the melanocyte precursors. Conserved developmental expression in the melanocyte lineage of both Pax3 and Pax7 was evidenced in chick and quail, but only Pax3 in mouse and rat. |
| Databáze: | OpenAIRE |
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